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Importantly, suspected adverse reactions to any medicine including unlicensed, counterfeit, or unregulated products can and should be reported to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk or through the Yellow Card app

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Global: the UK (MHRA), EU (EMA), and Australia (TGA) follow the same split approved medicines yes, unapproved peptides no

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Astrup A, Toubro S, Cannon S, Hein P, Breum L, Madsen J (1990) Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers